Formulation of Antimicrobial Topical Gel Loaded with Stellaria Media Extract

Abstract

Topical gels prepared from herbal extracts are safer and more efficient than synthetic topical gels. This study is performed to formulate an antimicrobial topical gel made of plant extract Stellaria media. The Stellaria media have many pharmacological activities such as antifungal, anti-inflammatory, anti-leishmanial, and antimicrobial. The extracts of Stellaria media were obtained from maceration and phytochemical analysis was performed and analyzed the phytochemical chemical present in the Stellaria media. The Stellaria media was loaded in the gel base with the gelling agent carbopol-940 and other excipients. Evaluation studies like viscosity, pH, spreadability, and homogeneity were determined. The antimicrobial activity was studied using disk diffusion method using Gram-positive bacteria (S.aures) and Gram-negative bacteria (E.coli). The zone of inhibition was studied, and the outcomes were comparatively efficient. This implies that Stellaria media-loaded topical gels can be a potential antimicrobial agent.